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Beta cell MHC class I is a late requirement for diabetes

Type 1 diabetes occurs as a result of an autoimmune attack on the insulin-producing beta cells. Although CD8 T cells have been implicated both early and late in this process, the requirement for direct interaction between these cells and MHC class I on the beta cells has not been demonstrated. By us...

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Hlavní autoři: Hamilton-Williams, Emma E., Palmer, Stephanie E., Charlton, Brett, Slattery, Robyn M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC164508/
https://ncbi.nlm.nih.gov/pubmed/12750472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1131954100
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