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Structural and biochemical studies of p21(Ras) S-nitrosylation and nitric oxide-mediated guanine nucleotide exchange

Ras is a guanine nucleotide-binding protein that cycles between inactive GDP-bound and active GTP-bound states to regulate a diverse array of cellular processes, including cell growth, apoptosis, and differentiation. The guanine nucleotide-bound state of Ras is tightly maintained by regulatory facto...

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Detalhes bibliográficos
Main Authors: Williams, Jason G., Pappu, Kamesh, Campbell, Sharon L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164454/
https://ncbi.nlm.nih.gov/pubmed/12740440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1037299100
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