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The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity

Inducible costimulatory molecule (ICOS) plays a pivotal role in T cell activation and Th1/Th2 differentiation. ICOS blockade has disparate effects on immune responses depending on the timing of blockade. Its role in transplantation immunity, however, remains incompletely defined. We used a vasculari...

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Détails bibliographiques
Auteurs principaux: Harada, Hiroshi, Salama, Alan D., Sho, Masayuki, Izawa, Atsushi, Sandner, Sigrid E., Ito, Toshiro, Akiba, Hisaya, Yagita, Hideo, Sharpe, Arlene H., Freeman, Gordon J., Sayegh, Mohamed H.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC164288/
https://ncbi.nlm.nih.gov/pubmed/12865411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317008
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