Application of a mathematical model to prevent in vivo amplification of antibiotic-resistant bacterial populations during therapy

The worldwide increase in the prevalence of multi-antibiotic–resistant bacteria has threatened the physician’s ability to provide appropriate therapy for infections. The relationship between antimicrobial drug concentration and infecting pathogen population reduction is of primary interest. Using da...

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Pubblicato in:	J Clin Invest
Autori principali:	Jumbe, Nelson, Louie, Arnold, Leary, Robert, Liu, Weiguo, Deziel, Mark R., Tam, Vincent H., Bachhawat, Reetu, Freeman, Christopher, Kahn, James B., Bush, Karen, Dudley, Michael N., Miller, Michael H., Drusano, George L.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 2003
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164285/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12865415/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI16814
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