The antitumor effects of IFN-α are abrogated in a STAT1-deficient mouse

IFN-α activates the signal transducer and activator of transcription (STAT) family of proteins; however, it is unknown whether IFN-α exerts its antitumor actions primarily through a direct effect on malignant cells or by stimulating the immune system. To investigate the contribution of STAT1 signali...

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Autors principals: Lesinski, Gregory B., Anghelina, Mirela, Zimmerer, Jason, Bakalakos, Timothy, Badgwell, Brian, Parihar, Robin, Hu, Yan, Becknell, Brian, Abood, Gerard, Chaudhury, Abhik Ray, Magro, Cynthia, Durbin, Joan, Carson, William E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2003
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC164283/
https://ncbi.nlm.nih.gov/pubmed/12865406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200316603
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