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Global Structural Changes in Hepatitis B Virus Capsids Induced by the Assembly Effector HAP1

Hepatitis B virus (HBV) is a leading cause of liver disease and hepatocellular carcinoma; over 400 million people are chronically infected with HBV. Specific anti-HBV treatments, like most antivirals, target enzymes that are similar to host proteins. Virus capsid protein has no human homolog, making...

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Detalhes bibliográficos
Main Authors: Bourne, Christina R., Finn, M. G., Zlotnick, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1642186/
https://ncbi.nlm.nih.gov/pubmed/16943288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00933-06
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