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Trapping of Hepatitis B Virus capsid assembly intermediates by phenylpropenamide assembly accelerators

Understanding the biological self-assembly process of virus capsids is key to understanding the viral life cycle, as well as serving as a platform for the design of assembly-based antiviral drugs. Here we identify and characterize the phenylpropenamide family of small molecules, known to have antivi...

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Detalhes bibliográficos
Main Authors: Katen, Sarah P., Chirapu, Srinivas Reddy, Finn, M.G., Zlotnick, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003741/
https://ncbi.nlm.nih.gov/pubmed/20845949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb100275b
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