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Evolution of Intermediates during Capsid Assembly of Hepatitis B Virus with Phenylpropenamide-based Antivirals

The self-assembly of virus capsids is a potential target for antivirals due to its importance in the virus lifecycle. Here, we investigate the effect of phenylpropenamide derivatives B-21 and AT-130 on the assembly of hepatitis B virus (HBV) core protein. Phenylpropenamides are widely believed to yi...

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Vydáno v:ACS Infect Dis
Hlavní autoři: Kondylis, Panagiotis, Schlicksup, Christopher J., Katen, Sarah P., Lee, Lye Siang, Zlotnick, Adam, Jacobson, Stephen C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510601/
https://ncbi.nlm.nih.gov/pubmed/30616343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.8b00290
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