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Pharmacokinetics and safety of a single dose of stavudine (d4T) in patients with severe hepatic impairment.

This open-label study enrolled five subjects with biopsy-proven cirrhosis and moderate to severe hepatic impairment (Child-Pugh classification grade B or C) and five age- and gender-matched controls. All subjects received a single 40-mg oral dose of stavudine (d4T). Stavudine pharmacokinetics in sub...

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Bibliografski detalji
Glavni autori: Schaad, H J, Petty, B G, Grasela, D M, Christofalo, B, Raymond, R, Stewart, M
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC164213/
https://ncbi.nlm.nih.gov/pubmed/9420063
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