Murine Hepatitis Virus Strain 1 Produces a Clinically Relevant Model of Severe Acute Respiratory Syndrome in A/J Mice

Severe acute respiratory syndrome (SARS) is a life-threatening infectious disease which has been difficult to study and treat because of the lack of a readily available animal model. Intranasal infection of A/J mice with the coronavirus murine hepatitis virus strain 1 (MHV-1) produced pulmonary path...

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Main Authors: De Albuquerque, Nadine, Baig, Ehtesham, Ma, Xuezhong, Zhang, Jianhua, He, William, Rowe, Andrea, Habal, Marlena, Liu, Mingfeng, Shalev, Itay, Downey, Gregory P., Gorczynski, Reginald, Butany, Jagdish, Leibowitz, Julian, Weiss, Susan R., McGilvray, Ian D., Phillips, M. James, Fish, Eleanor N., Levy, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1641767/
https://ncbi.nlm.nih.gov/pubmed/17041219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00747-06
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