Targeted delivery of ribavirin improves outcome of murine viral fulminant hepatitis via enhanced anti‐viral activity

Side effects of interferon–ribavirin combination therapy limit the sustained viral response achievable in hepatitis C virus (HCV) patients. Coupling ribavirin to macromolecular carriers that target the drug to the liver would reduce systemic complications. The aim of this study was to evaluate the e...

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Vydáno v:Hepatology
Hlavní autoři: Levy, Gary A., Adamson, Gord, Phillips, M. James, Scrocchi, Louise A., Fung, Laisum, Biessels, Pieter, Ng, Nancy F., Ghanekar, Anand, Rowe, Andrea, Ma, Max Xuezhong, Levy, Adam, Koscik, Cheryl, He, William, Gorczynski, Reginald, Brookes, Steve, Woods, Caroline, McGilvray, Ian D., Bell, David
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley Subscription Services, Inc., A Wiley Company 2006
Témata:
Viral Hepatitis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7165489/
https://ncbi.nlm.nih.gov/pubmed/16496340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.21072
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