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Targeted delivery of ribavirin improves outcome of murine viral fulminant hepatitis via enhanced anti‐viral activity

Side effects of interferon–ribavirin combination therapy limit the sustained viral response achievable in hepatitis C virus (HCV) patients. Coupling ribavirin to macromolecular carriers that target the drug to the liver would reduce systemic complications. The aim of this study was to evaluate the e...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Levy, Gary A., Adamson, Gord, Phillips, M. James, Scrocchi, Louise A., Fung, Laisum, Biessels, Pieter, Ng, Nancy F., Ghanekar, Anand, Rowe, Andrea, Ma, Max Xuezhong, Levy, Adam, Koscik, Cheryl, He, William, Gorczynski, Reginald, Brookes, Steve, Woods, Caroline, McGilvray, Ian D., Bell, David
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7165489/
https://ncbi.nlm.nih.gov/pubmed/16496340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.21072
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