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Pharmacokinetic interaction of megestrol acetate with zidovudine in human immunodeficiency virus-infected patients.

This nonrandomized, two-period crossover study was performed to assess whether concomitant administration of megestrol acetate influences the steady-state pharmacokinetics of zidovudine and its inactive 5'-O-glucuronide metabolite. Twelve HIV-positive, asymptomatic male volunteers received a 100-mg...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Van Harken, D R, Pei, J C, Wagner, J, Pike, I M
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164148/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371353/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.11.2480
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