Absence of effect of trimethoprim-sulfamethoxazole on pharmacokinetics of zidovudine in patients infected with human immunodeficiency virus.

Pharmacokinetic parameters of zidovudine (ZDV) were not altered in 16 patients receiving concomitant therapy with ZDV and trimethoprim-sulfamethoxazole by oral administration. ZDV areas under the concentration-time curves were (means +/- standard deviations) 1.80 +/- 0.70 and 1.69 +/- 0.64 microgram...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Cañas, E, Pachon, J, Garcia-Pesquera, F, Castillo, J R, Viciana, P, Cisneros, J M, Jimenez-Mejias, M E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163089/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8787912/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.1.230
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