Pharmacokinetics of concomitantly administered foscarnet and zidovudine for treatment of human immunodeficiency virus infection (AIDS Clinical Trials Group protocol 053).

Foscarnet and zidovudine (ZDV) pharmacokinetic parameters were not altered in five patients receiving 14 days of concomitant therapy. Foscarnet clearance in plasma averaged (+/- standard deviation) 0.16 +/- 0.03 and 0.13 +/- 0.05 liter/h/kg of body weight in the absence and presence of ZDV. ZDV para...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Aweeka, F T, Gambertoglio, J G, van der Horst, C, Raasch, R, Jacobson, M A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192046/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1416864/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.8.1773
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