Inhibition of replication of hepatitis B virus by cytallene in vitro.

The acyclic cytosine nucleoside analog cytallene [1-(4'-hydroxy-1',2'-butadienyl)cytosine], which has both (+)- and (-)-enantiomers, was evaluated for its anti-hepatitis B virus (HBV) activity in 2.2.15 cells and was found to have potent activity against HBV DNA synthesis. The R-(-)-enantiomer was f...

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Publicat a:	Antimicrob Agents Chemother
Autors principals:	Zhu, Y L, Pai, S B, Liu, S H, Grove, K L, Jones, B C, Simons, C, Zemlicka, J, Cheng, Y C
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1997
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163999/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9257755/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.8.1755
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