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Mechanism of inhibition of duck hepatitis B virus polymerase by (-)-beta-L-2',3'-dideoxy-3'-thiacytidine.

We have used the endogenous reverse transcriptase reaction of viral core particles from duck liver to elucidate the mechanism of inhibition of duck hepatitis B virus (DHBV) replication by the nucleoside analog (-)-beta-L-2',3'-dideoxy-3'-thiacytidine (3TC). As is the case in human immunodeficiency v...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Severini, A, Liu, X Y, Wilson, J S, Tyrrell, D L
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162757/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7492080/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.7.1430
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