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Inhibition of replication of hepatitis B virus by cytallene in vitro.

The acyclic cytosine nucleoside analog cytallene [1-(4'-hydroxy-1',2'-butadienyl)cytosine], which has both (+)- and (-)-enantiomers, was evaluated for its anti-hepatitis B virus (HBV) activity in 2.2.15 cells and was found to have potent activity against HBV DNA synthesis. The R-(-)-enantiomer was f...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphov: Zhu, Y L, Pai, S B, Liu, S H, Grove, K L, Jones, B C, Simons, C, Zemlicka, J, Cheng, Y C
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Microbiology (ASM) 1997
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163999/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9257755/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.8.1755
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