Inhibitors of delta24(25) sterol methyltransferase block sterol synthesis and cell proliferation in Pneumocystis carinii.
Detailed analysis of the endogenous sterol content of purified Pneumocystis carinii preparations by gas-liquid chromatography coupled to mass spectrometry suggested that this parasite can both synthesize de novo steroid skeletons (to produce delta7 sterols) and take them from the infected host (lead...
Sparad:
| I publikationen: | Antimicrob Agents Chemother |
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| Huvudupphov: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
American Society for Microbiology (ASM)
1997
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163934/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9210660/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.7.1428 |
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