Pneumocysterol [(24Z)-ethylidenelanost-8-en-3β-ol], a rare sterol detected in the opportunistic pathogen Pneumocystis carinii hominis: Structural identity and chemical synthesis

Pneumocystis carinii pneumonia (PcP) remains among the most prevalent opportunistic infections among AIDS patients. Currently, drugs used clinically for deep mycosis act by binding ergosterol or disrupting its biosynthesis. Although classified as a fungus, P. carinii lacks ergosterol. Instead, the p...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Kaneshiro, Edna S., Amit, Zunika, Swonger, Mardie M., Kreishman, George P., Brooks, Elwood E., Kreishman, Mara, Jayasimhulu, Koka, Parish, Edward J., Sun, Hang, Kizito, Stephen A., Beach, David H.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1999
Materias:	Biological Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15099/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9874778/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.1.97
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