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Pneumocysterol [(24Z)-ethylidenelanost-8-en-3β-ol], a rare sterol detected in the opportunistic pathogen Pneumocystis carinii hominis: Structural identity and chemical synthesis

Pneumocystis carinii pneumonia (PcP) remains among the most prevalent opportunistic infections among AIDS patients. Currently, drugs used clinically for deep mycosis act by binding ergosterol or disrupting its biosynthesis. Although classified as a fungus, P. carinii lacks ergosterol. Instead, the p...

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Sábháilte in:
Foilsithe in:Proc Natl Acad Sci U S A
Príomhchruthaitheoirí: Kaneshiro, Edna S., Amit, Zunika, Swonger, Mardie M., Kreishman, George P., Brooks, Elwood E., Kreishman, Mara, Jayasimhulu, Koka, Parish, Edward J., Sun, Hang, Kizito, Stephen A., Beach, David H.
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: National Academy of Sciences 1999
Ábhair:
Biological Sciences
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15099/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9874778/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.1.97
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