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New quinoline di-Mannich base compounds with greater antimalarial activity than chloroquine, amodiaquine, or pyronaridine.

We have compared the ex vivo antimalarial activity of 12 new quinoline di-Mannich base compounds containing the 7-dichloroquinoline or 7-trifluoromethylquinoline nucleus with amodiaquine, chloroquine, and pyronaridine using the Saimiri-bioassay model. Each compound was administered orally (30 mg/kg...

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Sonraí Bibleagrafaíochta
Main Authors: Kotecka, B M, Barlin, G B, Edstein, M D, Rieckmann, K H
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1997
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC163917/
https://ncbi.nlm.nih.gov/pubmed/9174201
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