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Pharmacokinetics of gentamicin at traditional versus high doses: implications for once-daily aminoglycoside dosing.

Two doses of gentamicin (2 and 7 mg/kg of body weight) were administered to 11 healthy volunteers in a randomized, crossover single-dose study to compare their pharmacokinetics. Doses were infused over 1 h with a syringe infusion pump, and 14 concentrations in sera were obtained over an 8-h period....

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Detalhes bibliográficos
Main Authors: Demczar, D J, Nafziger, A N, Bertino, J S
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC163859/
https://ncbi.nlm.nih.gov/pubmed/9145878
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