Pharmacokinetics of gentamicin at traditional versus high doses: implications for once-daily aminoglycoside dosing.
Two doses of gentamicin (2 and 7 mg/kg of body weight) were administered to 11 healthy volunteers in a randomized, crossover single-dose study to compare their pharmacokinetics. Doses were infused over 1 h with a syringe infusion pump, and 14 concentrations in sera were obtained over an 8-h period....
Enregistré dans:
| Publié dans: | Antimicrob Agents Chemother |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
1997
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163859/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9145878/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.5.1115 |
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