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Pharmacokinetics of gentamicin at traditional versus high doses: implications for once-daily aminoglycoside dosing.
Two doses of gentamicin (2 and 7 mg/kg of body weight) were administered to 11 healthy volunteers in a randomized, crossover single-dose study to compare their pharmacokinetics. Doses were infused over 1 h with a syringe infusion pump, and 14 concentrations in sera were obtained over an 8-h period....
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1997
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC163859/ https://ncbi.nlm.nih.gov/pubmed/9145878 |
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