Pharmacokinetics of gentamicin at traditional versus high doses: implications for once-daily aminoglycoside dosing.
Two doses of gentamicin (2 and 7 mg/kg of body weight) were administered to 11 healthy volunteers in a randomized, crossover single-dose study to compare their pharmacokinetics. Doses were infused over 1 h with a syringe infusion pump, and 14 concentrations in sera were obtained over an 8-h period....
Guardat en:
| Publicat a: | Antimicrob Agents Chemother |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163859/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9145878/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.5.1115 |
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