Antiviral activity of the dihydropyrone PNU-140690, a new nonpeptidic human immunodeficiency virus protease inhibitor.

PNU-140690 is a member of a new class of nonpeptidic human immunodeficiency virus (HIV) protease inhibitors (sulfonamide-containing 5,6-dihydro-4-hydroxy-2-pyrones) discovered by structure-based design. PNU-140690 has excellent potency against a variety of HIV type 1 (HIV-1) laboratory strains and c...

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Detalhes bibliográficos
Main Authors: Poppe, S M, Slade, D E, Chong, K T, Hinshaw, R R, Pagano, P J, Markowitz, M, Ho, D D, Mo, H, Gorman, R R, Dueweke, T J, Thaisrivongs, S, Tarpley, W G
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC163850/
https://ncbi.nlm.nih.gov/pubmed/9145869
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