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Antiviral activity of the dihydropyrone PNU-140690, a new nonpeptidic human immunodeficiency virus protease inhibitor.

PNU-140690 is a member of a new class of nonpeptidic human immunodeficiency virus (HIV) protease inhibitors (sulfonamide-containing 5,6-dihydro-4-hydroxy-2-pyrones) discovered by structure-based design. PNU-140690 has excellent potency against a variety of HIV type 1 (HIV-1) laboratory strains and c...

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Sparad:
I publikationen:Antimicrob Agents Chemother
Huvudupphov: Poppe, S M, Slade, D E, Chong, K T, Hinshaw, R R, Pagano, P J, Markowitz, M, Ho, D D, Mo, H, Gorman, R R, Dueweke, T J, Thaisrivongs, S, Tarpley, W G
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Microbiology (ASM) 1997
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163850/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9145869/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.5.1058
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