Alterations in the GyrA subunit of DNA gyrase and the ParC subunit of topoisomerase IV in quinolone-resistant clinical isolates of Klebsiella pneumoniae.

We determined a partial sequence of the Klebsiella pneumoniae parC gene, including the region analogous to the quinolone resistance-determining region of the Escherichia coli gyrA gene, and examined 26 clinical strains of K. pneumoniae for an association of alterations in GyrA and ParC with suscepti...

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Bibliographic Details
Main Authors: Deguchi, T, Fukuoka, A, Yasuda, M, Nakano, M, Ozeki, S, Kanematsu, E, Nishino, Y, Ishihara, S, Ban, Y, Kawada, Y
Format: Artigo
Language:Inglês
Published: 1997
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC163775/
https://ncbi.nlm.nih.gov/pubmed/9056017
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