Alterations in the GyrA subunit of DNA gyrase and the ParC subunit of topoisomerase IV in quinolone-resistant clinical isolates of Klebsiella pneumoniae.

We determined a partial sequence of the Klebsiella pneumoniae parC gene, including the region analogous to the quinolone resistance-determining region of the Escherichia coli gyrA gene, and examined 26 clinical strains of K. pneumoniae for an association of alterations in GyrA and ParC with suscepti...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Deguchi, T, Fukuoka, A, Yasuda, M, Nakano, M, Ozeki, S, Kanematsu, E, Nishino, Y, Ishihara, S, Ban, Y, Kawada, Y
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1997
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163775/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9056017/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.3.699
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