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Complete correction of murine Artemis immunodeficiency by lentiviral vector-mediated gene transfer

Artemis gene mutations are responsible for the development of a severe combined immunodeficiency [radiation-sensitive (RS) SCID] characterized by a severe B and T cell deficiency and a normal natural killer cell population. To establish the feasibility of a gene therapy approach to the treatment of...

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Autors principals: Mostoslavsky, Gustavo, Fabian, Attila J., Rooney, Sean, Alt, Frederick W., Mulligan, Richard C.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1637595/
https://ncbi.nlm.nih.gov/pubmed/17062750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608130103
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