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Cytotoxicity Associated with Artemis Overexpression After Lentiviral Vector-Mediated Gene Transfer
Artemis is a hairpin-opening endonuclease involved in nonhomologous end-joining and V(D)J recombination. Deficiency of Artemis results in radiation-sensitive severe combined immunodeficiency (SCID) characterized by complete absence of T and B cells due to an arrest at the receptor recombination stag...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2938362/ https://ncbi.nlm.nih.gov/pubmed/20163250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2009.162 |
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