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Characterization of the Human Artemis Promoter by Heterologous Gene Expression In Vitro and In Vivo
Artemis is an endonucleolytic enzyme involved in nonhomologous double-strand break repair and V(D)J recombination. Deficiency of Artemis results in a B(−) T(−) radiosensitive severe combined immunodeficiency, which may potentially be treatable by Artemis gene transfer into hematopoietic stem cells....
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Mary Ann Liebert, Inc.
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3183654/ https://ncbi.nlm.nih.gov/pubmed/21663454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2011.1244 |
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