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Macrophage inhibitory cytokine 1 mediates a p53-dependent protective arrest in S phase in response to starvation for DNA precursors

p53 is essential for the cellular responses to DNA damage that help to maintain genomic stability. Protective p53-dependent cell-cycle checkpoints are activated in response to a wide variety of stresses, including not only DNA damage but also arrest of DNA synthesis and of mitosis. In addition to it...

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Hlavní autoři: Agarwal, Mukesh K., Hastak, Kedar, Jackson, Mark W., Breit, Samuel N., Stark, George R., Agarwal, Munna L.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1637573/
https://ncbi.nlm.nih.gov/pubmed/17050687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607210103
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