Crystal structure of a photoactivated deprotonated intermediate of rhodopsin

The changes that lead to activation of G protein-coupled receptors have not been elucidated at the structural level. In this work we report the crystal structures of both ground state and a photoactivated deprotonated intermediate of bovine rhodopsin at a resolution of 4.15 Å. In the photoactivated...

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Bibliografiske detaljer
Main Authors: Salom, David, Lodowski, David T., Stenkamp, Ronald E., Trong, Isolde Le, Golczak, Marcin, Jastrzebska, Beata, Harris, Tim, Ballesteros, Juan A., Palczewski, Krzysztof
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1637547/
https://ncbi.nlm.nih.gov/pubmed/17060607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608022103
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