Diarylsulfones, a novel class of human immunodeficiency virus type 1 integrase inhibitors.

A majority of reported human immunodeficiency virus type 1 integrase (HIV-1 IN) inhibitors are polyhydroxylated aromatic compounds containing two phenyl rings separated by aliphatic or aromatic linkers. Most inhibitors possessing a catechol moiety exhibit considerable toxicity in cellular assays. In...

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Bibliografiske detaljer
Main Authors: Neamati, N, Mazumder, A, Zhao, H, Sunder, S, Burke, T R, Schultz, R J, Pommier, Y
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC163718/
https://ncbi.nlm.nih.gov/pubmed/9021196
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