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Characterisation of a transgenic mouse expressing R122H human cationic trypsinogen

BACKGROUND: The R122H mutation of the cationic trypsinogen was found in patients with hereditary pancreatitis. A transgenic animal carrying this mutation could be useful as a genetic model system of pancreatitis. METHODS: Mice transgenic for the human R122H cationic trypsinogen were generated using...

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Détails bibliographiques
Auteurs principaux: Selig, Lena, Sack, Ulrich, Gaiser, Sebastian, Klöppel, Günter, Savkovic, Vuk, Mössner, Joachim, Keim, Volker, Bödeker, Hans
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1637108/
https://ncbi.nlm.nih.gov/pubmed/17069643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-6-30
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