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Specific Recognition of ZNF217 and Other Zinc Finger Proteins at a Surface Groove of C-Terminal Binding Proteins

Numerous transcription factors recruit C-terminal binding protein (CtBP) corepressors. We show that the large zinc finger protein ZNF217 contacts CtBP. ZNF217 is encoded by an oncogene frequently amplified in tumors. ZNF217 contains a typical Pro-X-Asp-Leu-Ser (PXDLS) motif that binds in CtBP's...

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Detalhes bibliográficos
Main Authors: Quinlan, Kate G. R., Nardini, Marco, Verger, Alexis, Francescato, Pierangelo, Yaswen, Paul, Corda, Daniela, Bolognesi, Martino, Crossley, Merlin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636751/
https://ncbi.nlm.nih.gov/pubmed/16940172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00680-06
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