New Insights into DNA Recognition by Zinc Fingers Revealed by Structural Analysis of the Oncoprotein ZNF217

Classical zinc fingers (ZFs) are one of the most abundant and best characterized DNA-binding domains. Typically, tandem arrays of three or more ZFs bind DNA target sequences with high affinity and specificity, and the mode of DNA recognition is sufficiently well understood that tailor-made ZF-based...

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Autors principals: Vandevenne, Marylène, Jacques, David A., Artuz, Crisbel, Nguyen, Cuong Dinh, Kwan, Ann H. Y., Segal, David J., Matthews, Jacqueline M., Crossley, Merlin, Guss, J. Mitchell, Mackay, Joel P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Protein Structure and Folding
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624442/
https://ncbi.nlm.nih.gov/pubmed/23436653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.441451
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