Role of the C-Terminal Binding Protein PXDLS Motif Binding Cleft in Protein Interactions and Transcriptional Repression

C-terminal binding proteins (CtBPs) are multifunctional proteins that can mediate gene repression. CtBPs contain a cleft that binds Pro-X-Asp-Leu-Ser (PXDLS) motifs. PXDLS motifs occur in numerous transcription factors and in effectors of gene repression, such as certain histone deacetylases. CtBPs...

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Main Authors: Quinlan, Kate G. R., Verger, Alexis, Kwok, Alister, Lee, Stella H. Y., Perdomo, José, Nardini, Marco, Bolognesi, Martino, Crossley, Merlin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636740/
https://ncbi.nlm.nih.gov/pubmed/16940173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00445-06
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