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Lck SH3 Domain Function Is Required for T-Cell Receptor Signals Regulating Thymocyte Development

Thymocyte development is shaped by signals from the T-cell antigen receptor. The strength of receptor signaling determines developmental progression as well as deletion of self-reactive T cells. Receptor stimulation of the extracellular signal-regulated kinase (ERK) pathway plays an important regula...

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Autori principali: Rudd, Meghan L., Tua-Smith, Alymarie, Straus, David B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636743/
https://ncbi.nlm.nih.gov/pubmed/16923964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00968-06
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