Role for RAD18 in Homologous Recombination in DT40 Cells

RAD18 is an E3 ubiquitin ligase that catalyzes the monoubiquitination of PCNA, a modification central to DNA damage bypass and postreplication repair in both yeast and vertebrates. Although current evidence suggests that homologous recombination provides an essential backup in vertebrate rad18 mutan...

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Bibliographic Details
Main Authors: Szüts, Dávid, Simpson, Laura J., Kabani, Sarah, Yamazoe, Mitsuyoshi, Sale, Julian E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636725/
https://ncbi.nlm.nih.gov/pubmed/16923963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01291-06
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