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Role for RAD18 in Homologous Recombination in DT40 Cells
RAD18 is an E3 ubiquitin ligase that catalyzes the monoubiquitination of PCNA, a modification central to DNA damage bypass and postreplication repair in both yeast and vertebrates. Although current evidence suggests that homologous recombination provides an essential backup in vertebrate rad18 mutan...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1636725/ https://ncbi.nlm.nih.gov/pubmed/16923963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01291-06 |
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