Functional Identification of Api5 as a Suppressor of E2F-Dependent Apoptosis In Vivo

Retinoblastoma protein and E2-promoter binding factor (E2F) family members are important regulators of G1-S phase progression. Deregulated E2F also sensitizes cells to apoptosis, but this aspect of E2F function is poorly understood. Studies of E2F-induced apoptosis have mostly been carried out in ti...

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Bibliographic Details
Main Authors: Morris, Erick J, Michaud, William A, Ji, Jun-Yuan, Moon, Nam-Sung, Rocco, James W, Dyson, Nicholas J
Format: Artigo
Language:Inglês
Published: Public Library of Science 2006
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636698/
https://ncbi.nlm.nih.gov/pubmed/17112319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0020196
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