Transcriptional and post-transcriptional regulation of retrotransposons IAP and MuERV-L affect pluripotency of mice ES cells

BACKGROUND: In the mouse, culture of embryonic stem (ES) cells may decrease their pluripotency and give rise to foetal abnormalities in recipient embryos. These abnormalities are frequently associated with both, chromosome abnormalities or epigenetic alteration of imprinting genes; however, little i...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ramírez, Miguel A, Pericuesta, Eva, Fernandez-Gonzalez, Raul, Moreira, Pedro, Pintado, Belen, Gutierrez-Adan, Alfonso
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2006
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636644/
https://ncbi.nlm.nih.gov/pubmed/17090336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-4-55
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