The proximal promoter region of mTert is sufficient to regulate telomerase activity in ES cells and transgenic animals

BACKGROUND: The reverse transcriptase of telomerase (Tert) controls telomerase activity maintaining the end of linear chromosomes in eukaryotic cells. Telomerase function is highly active in undifferentiated multipotent stem cells, decreases with cell differentiation and is generally absent from mos...

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Detalhes bibliográficos
Main Authors: Pericuesta, Eva, Ramírez, Miguel Angel, Villa-Diaz, Ana, Relaño-Gines, Aroa, Maria Torres, Juan, Nieto, Marta, Pintado, Belen, Gutiérrez-Adán, Alfonso
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1402293/
https://ncbi.nlm.nih.gov/pubmed/16457732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-4-5
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