Transcriptional and post-transcriptional regulation of retrotransposons IAP and MuERV-L affect pluripotency of mice ES cells

BACKGROUND: In the mouse, culture of embryonic stem (ES) cells may decrease their pluripotency and give rise to foetal abnormalities in recipient embryos. These abnormalities are frequently associated with both, chromosome abnormalities or epigenetic alteration of imprinting genes; however, little i...

Full description

Saved in:
Bibliographic Details
Main Authors: Ramírez, Miguel A, Pericuesta, Eva, Fernandez-Gonzalez, Raul, Moreira, Pedro, Pintado, Belen, Gutierrez-Adan, Alfonso
Format: Artigo
Language:Inglês
Published: BioMed Central 2006
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636644/
https://ncbi.nlm.nih.gov/pubmed/17090336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-4-55
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items