Transcriptional and post-transcriptional regulation of retrotransposons IAP and MuERV-L affect pluripotency of mice ES cells

BACKGROUND: In the mouse, culture of embryonic stem (ES) cells may decrease their pluripotency and give rise to foetal abnormalities in recipient embryos. These abnormalities are frequently associated with both, chromosome abnormalities or epigenetic alteration of imprinting genes; however, little i...

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Main Authors: Ramírez, Miguel A, Pericuesta, Eva, Fernandez-Gonzalez, Raul, Moreira, Pedro, Pintado, Belen, Gutierrez-Adan, Alfonso
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2006
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636644/
https://ncbi.nlm.nih.gov/pubmed/17090336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-4-55
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