Replication of vertebrate mitochondrial DNA entails transient ribonucleotide incorporation throughout the lagging strand

Using two-dimensional agarose gel electrophoresis, we show that mitochondrial DNA (mtDNA) replication of birds and mammals frequently entails ribonucleotide incorporation throughout the lagging strand (RITOLS). Based on a combination of two-dimensional agarose gel electrophoretic analysis and mappin...

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Hauptverfasser: Yasukawa, Takehiro, Reyes, Aurelio, Cluett, Tricia J, Yang, Ming-Yao, Bowmaker, Mark, Jacobs, Howard T, Holt, Ian J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636616/
https://ncbi.nlm.nih.gov/pubmed/17066082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601392
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