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Template disruptions and failure of double Holliday junction dissolution during double-strand break repair in Drosophila BLM mutants

Previous biochemical studies of the BLM gene product have shown its ability in conjunction with topoisomerase IIIα to resolve double Holliday structures through a process called “dissolution.” This process could prevent crossing over during repair of double-strand breaks. We report an analysis of th...

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Autores principales: Johnson-Schlitz, Dena, Engels, William R.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636541/
https://ncbi.nlm.nih.gov/pubmed/17075047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607904103
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