The HRDC domain of BLM is required for the dissolution of double Holliday junctions

Bloom's syndrome is a hereditary cancer-predisposition disorder resulting from mutations in the BLM gene. In humans, BLM encodes one of five members of the RecQ helicase family. One function of BLM is to act in concert with topoisomerase IIIα (TOPO IIIα) to resolve recombination intermediates c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wu, Leonard, Lung Chan, Kok, Ralf, Christine, Bernstein, Douglas A, Garcia, Patrick L, Bohr, Vilhelm A, Vindigni, Alessandro, Janscak, Pavel, Keck, James L, Hickson, Ian D
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2005
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1176466/
https://ncbi.nlm.nih.gov/pubmed/15990871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600740
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