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Structural and functional analysis of the MutS C-terminal tetramerization domain

The Escherichia coli DNA mismatch repair (MMR) protein MutS is essential for the correction of DNA replication errors. In vitro, MutS exists in a dimer/tetramer equilibrium that is converted into a monomer/dimer equilibrium upon deletion of the C-terminal 53 amino acids. In vivo and in vitro data ha...

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Détails bibliographiques
Auteurs principaux: Manelyte, Laura, Urbanke, Claus, Giron-Monzon, Luis, Friedhoff, Peter
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636413/
https://ncbi.nlm.nih.gov/pubmed/17012287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl489
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