MUMMALS: multiple sequence alignment improved by using hidden Markov models with local structural information

We have developed MUMMALS, a program to construct multiple protein sequence alignment using probabilistic consistency. MUMMALS improves alignment quality by using pairwise alignment hidden Markov models (HMMs) with multiple match states that describe local structural information without exploiting e...

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Bibliografske podrobnosti
Main Authors: Pei, Jimin, Grishin, Nick V.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2006
Teme:
Computational Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636350/
https://ncbi.nlm.nih.gov/pubmed/16936316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl514
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