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Role of DNA Polymerase IV in Escherichia coli SOS Mutator Activity

Constitutive expression of the SOS regulon in Escherichia coli recA730 strains leads to a mutator phenotype (SOS mutator) that is dependent on DNA polymerase V (umuDC gene product). Here we show that a significant fraction of this effect also requires DNA polymerase IV (dinB gene product).

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Detalhes bibliográficos
Main Authors: Kuban, Wojciech, Banach-Orlowska, Magdalena, Schaaper, Roel M., Jonczyk, Piotr, Fijalkowska, Iwona J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636302/
https://ncbi.nlm.nih.gov/pubmed/16980447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01088-06
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